How We Can Help

Meet Colin, age 11. Amenable to exon 45 skipping

You’ve got this.
We’ll make sure of it.

Starting a therapy like AMONDYS 45 can be a hopeful but complex time in your family’s life. We’re committed to ensuring that you know what to expect and have assistance at every step of the process. That’s why we developed SareptAssist, our comprehensive patient support program, designed to provide you with information to help you navigate starting and staying on AMONDYS 45.

Getting started with SareptAssist.

With your consent and signature, your doctor completes and sends in the SareptAssist Enrollment form. This form authorizes your Case Manager to start a benefits investigation on your current insurance coverage. Download the form to get the ball rolling.

SareptAssist is a resource available to those pursuing or currently utilizing one of Sarepta's approved products. SareptAssist is only available in the United States.

Questions?
Just give us a call at 1-888-SAREPTA (888-727-3782).
Case Managers are available
Monday – Friday
8:30 am – 6:30 pm ET.

Here's how SareptAssist can help:

One-on-one support from a dedicated Case Manager.

Once you enroll with SareptAssist, you’ll be connected to a dedicated Case Manager with experience in rare diseases, including knowledge of insurance plans and healthcare networks. While your doctor is your primary resource for discussing your medical needs, your Case Manager can be one of your key contacts for questions regarding insurance benefits, coordination of drug delivery, and access. Spanish-speaking Case Managers and interpreters for other languages are available.

Help navigate your insurance benefits.

Your Case Manager will help you understand how your insurance benefits work and can assist with the appeals process if your initial claim is denied. They can also provide information on options for financial assistance that you may qualify for.

Assistance with treatment locations.

You may receive AMONDYS 45 infusions at your doctor’s office, an infusion center, or at home. Your Case Manager will help by providing information on locations; discuss these options with your doctor to decide what’s best for your family.

Coordinating delivery of AMONDYS 45.

Once your insurance benefits are confirmed, SareptAssist will work with the providing specialty or hospital pharmacy to coordinate treatment access and drug delivery to your treatment location.

Support for the long run.

You can count on SareptAssist support throughout your treatment journey. Whether you are changing insurance companies, appealing a denial of coverage, or planning a well-deserved vacation, we’ll work with you to ensure that your treatment continues uninterrupted.

Information on financial assistance programs.

Your SareptAssist Case Manager can also provide information on financial support options you may qualify for, including the Co-Pay Assistance Program, Patient Assistance Program, and other support programs designed to assist with access to treatment.

Meet Nicholas, age 12. amenable to exon 45 skipping

Meet the SareptAssist Team.

Watch this video to learn more about the one-on-one personalized support offered to you by SareptAssist.

Questions about SareptAssist?

We are here to help.

Just give us a call at 1-888-SAREPTA (888-727-3782). Case Managers are available Monday – Friday 8:30 am – 6:30 pm ET.

SareptAssist is a resource available to those pursuing or currently utilizing one of Sarepta's approved products. SareptAssist is only available in the United States.

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“Our SareptAssist Case Manager was incredibly informed and helpful with every step of the process. From getting started on therapy to insurance reimbursement, they were invaluable.”

–Jake, Colin’s dad

Meet Jake, Colin's dad

Related FAQs

How can I connect with other families of children with Duchenne?

Several advocacy organizations offer Duchenne patients and families the opportunity to come together at events throughout the year. Find out more about Duchenne advocacy groups.

Will my insurance cover AMONDYS 45?

Once your child is prescribed AMONDYS 45, you may enroll in SareptAssist, our patient support program. Your Case Manager will start a benefits investigation on your current insurance plan and can help explain details about your coverage. How SareptAssist can help.

What is AMONDYS 45 (casimersen)?

AMONDYS 45 is used to treat patients with Duchenne muscular dystrophy (DMD) who have a confirmed mutation of the dystrophin gene that can be treated by skipping exon 45.

This indication is approved under accelerated approval based on an increase in dystrophin production in skeletal muscle observed in patients treated with AMONDYS 45. Continued approval for this indication may be contingent upon verification of a clinical benefit in confirmatory trials.

IMPORTANT SAFETY INFORMATION

Contraindications: Do not receive AMONDYS 45 if you are allergic to casimersen or any of the ingredients in AMONDYS 45. Serious allergic reactions to casimersen have included anaphylaxis, which may include difficulty breathing, tightness in the chest, and angioedema which may include swelling of the mouth, face, lips, or tongue.

Hypersensitivity Reactions: Serious allergic reactions, including angioedema and anaphylaxis, have occurred in patients who were treated with AMONDYS 45. Patients should seek immediate medical care should they experience signs and symptoms of allergic reactions. Your doctor will institute appropriate medical treatment which may include slowing, interrupting, or discontinuing the AMONDYS 45 infusion. Your doctor will monitor you until the condition resolves.

Kidney Toxicity and Monitoring: Damage to the kidneys was seen in animals who received casimersen. Although damage to the kidneys was not seen in clinical studies with AMONDYS 45, potentially fatal kidney damage has occurred with other drugs that work in a similar way. Your doctor may recommend urine and blood testing before starting treatment followed by urine testing every month and a blood test every 3 months to monitor your kidneys.

Adverse Reactions: Side effects occurring in at least 20% of patients treated with AMONDYS 45 and at least 5% more frequently than in patients who received an inactive intravenous (IV) infusion were (AMONDYS 45, placebo): upper respiratory tract infection (65%, 55%), cough (33%, 26%), fever (33%, 23%), headache (32%, 19%), joint pain (21%, 10%), and pain in mouth and throat (21%, 7%).

Other side effects that occurred in at least 10% of patients treated with AMONDYS 45 and at least 5% more frequently than patients who received an inactive IV infusion were: ear pain, nausea, ear infection, pain after injury, and dizziness and light-headedness.

What do I do if I have side effects?

Ask your healthcare provider for advice about any side effects that concern you.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088. You may also report side effects to Sarepta Therapeutics at 1-888-SAREPTA (1-888-727-3782).

The information provided here does not include all that is known about AMONDYS 45. To learn more, talk with your healthcare provider.

Before receiving this infusion, please see the full Prescribing Information for AMONDYS 45 (casimersen).